Associate Professor of Otorhinolaryngology, Department of Biomedical, Surgical and Dental Sciences, University of Milan
Medical Manager at the Otorhinolaryngology Unit, Fondazione I.R.C.C.S. Ca’ Granda Policlinico, Milan, Italy
Qualified as Professor of Otorhinolaryngology (2014)
EDUCATIONAL QUALIFICATIONS
- 1985: Scientific High School Diploma, G. Da Procida Scientific High School, Salerno, Italy.
- 1991: Degree in Medicine and Surgery, Catholic University del Sacro Cuore, Rome, Italy (110/110 cum laude).
- 1991: Qualified to practise surgery.
- 1995: Post-graduate specialisation in Otorhinolaryngology, University of Milan, Italy (110/110 cum laude).
- 1999: Post-graduate specialisation in Phoniatrics, University of Milan, Italy (110/110).
TRAINING
- 1990-1991: Attended the Department of General Surgery at Policlinico “A. Gemelli”, Rome, Italy;
- 1992-1995: Specialisation in Otorhinolaryngology, Milan, Italy;
- 1995-1999: Specialisation in Phoniatrics, Milan, Italy;
- 1996: Fellow at ENT Unit, Ospedale Maggiore Policlinico IRCCS, Milan, Italy;
- 2000-2005: Attended the Department of Oral and Maxillofacial Surgery, Guy’s Hospital, University of London, UK.
WORKING ACTIVITIES
- 1996-1999: Medical Manager, University ENT Clinic, Ospedale Maggiore Policlinico IRCCS, Milan, Italy;
- 1999: Medical Manager, ENT Unit, Azienda Ospedaliera di Lod, Lodi, Italy;
- 1999-2000: Medical Manager, University ENT Clinic, Ospedale Maggiore Policlinico IRCCS, Milan, Italy;
- 2001-2006: Medical Manager, University ENT Clinic, Ospedale L. Sacco, Milan, Italy;
- Since June 2006: University Researcher in Otorhinolaryngology, and clinician at ENT Unit, Fondazione IRCCS Ca’ Granda Policlinico, Milan, Italy.
- 2014-: Associate Professor of Otorhinolaryngology, University of Milan and Medical Manager, Fondazione IRCCS Ca’ Granda Policlinico of Milan, Italy
TEACHING ACTIVITIES
- Teacher of otorhinolaryngology as part of the integrated Medico-surgical Specialty course for the undergraduate degree course in Medicine and Surgery at Polo S. Donato, Faculty of Medicine and Surgery (2009-2017);
- Teacher of otorhinolaryngology as part of the integrated Medico-surgical Specialty course for the undergraduate degree course in Medicine and Surgery at Polo S. Giuseppe, Faculty of Medicine and Surgery (2007-2008);
- Teacher of otorhinolaryngology as part of the integrated Cervico-facial Diseases course for the undergraduate degree course in Odontics and Dental Prostheses, Faculty of Medicine and Surgery, University of Milan (2008-2017).
- Teacher of otorhinolaryngology as part of the integrated Interdisciplinary Specialist Surgical Sciences course for the undergraduate degree course in Orthoptics and Ophthalmological care, Faculty of Medicine and Surgery, University of Milan (2007-2012);
- Teacher of Ear and Upper Airways Diseases and Physiopathology of the Hearing and Vestibular apparatus for the undergraduate degree course in Audiometric Techniques, Faculty of Medicine and Surgery, University of Milan (2007-2017);
- Teacher of otorhinolaryngology as part of the integrated Clinical Neurological Sciences II course for the undergraduate degree course in Neurophysiopathology Techniques, Faculty of Medicine and Surgery, University of Milan (2007-2012).
- Contract Professor teaching Clinical ENT Pathology at the Post-graduate School of Otorhinolaryngology II (2002-2004).
- Assistant Professor teaching Clinical ENT Pathology at the Post-graduate School of Otorhinolaryngology II (2007-2014).
- Associate Professor teaching Clinical ENT Pathology at the Post-graduate School of Otorhinolaryngology II (2014-2017).
- Teacher of Anatomo-physiological Fundamentals of Pyschic Activity for the undergraduate degree course in Psychology at the University of Milan.
SCIENTIFIC ACYIVITIES
Principal research areas:
- Development of new diagnostic/therapeutic strategies in non-neoplastic salivary gland diseases, particularly obstructive disorders
- Development of sialendoscopy as a diagnostic and mini-invasive surgical method of treating obstructive disorders of the salivary duct system, particularly lithiasis;
- Development and diffusion of sialo-MR in the non-invasive diagnosis of salivary duct system anomalies;
- Use of salivary gland ultrasonography to select patients with obstructive salivary gland disorders for mini-invasive treatments such as extracorporeal salivary lithotripsy;
- Definition of new conservative treatments of salivary gland obstructions with the aim of preserving gland function (extracorporeal salivary lithotripsy, operative salivary gland sialendoscopy, functional video-assisted transoral surgery of salivary stones).
- The efficacy of botulin toxin injections in the non-invasive treatment of salivary disorders such as Frey syndrome, sialocele, recurrent parotitis, iatrogenic ductal stenoses, salivary fistulae, sialorrhea of neurological origin.
- Identification of genetic and acquired pro-thrombotic factors related to the etiopathogenesis of sudden deafness:
- PCR molecular analysis of genomic DNA in the search for possible correlations between the onset of sudden deafness and mutations in MTHFR genes, the pro-thrombin G20210A gene, the G1691A gene of Factor V Leiden, and the gene for GIYIIIaA1/A2 platelets; correlations with other factors such as hyper-homocysteinemia and hypercholesterolemia responsible for endothelial damage at the level of the cochlear microcirculation;
- The role of oxidative stress (particularly reactive oxygen species [ROS]) as an indicator of peripheral microvascular damage in patients affected by sudden deafness.
- Molecular and immunohistochemical study of oncogenic markers in malignant neoplasias of the upper airways and digestive pathways, particularly laryngeal squamous cell carcinomas
- Identification of molecular and immunohistochemical markers (e.g. cyclin D1, p53, bax, and bcl-2) predictive of the prognosis of malignant neoplasias of the upper airways and digestive pathways, particularly laryngeal squamous cell carcinomas. Correlations between factors such as cyclin D1 and cervical metastases, and their predictive role in occult metastatisation.
- The predictive role of proliferation markers such as ki67 in the evolution of low-grade laryngeal dysplasias to laryngeal carcinomas.
- The involvement of oncogenes such as p53, bax and bcl2 in the mechanisms of cell apoptosis in laryngeal squamous cell carcinomas and the possible practical consequence of using them to define therapeutic strategy (e.g. surgery vs radiotherapy).
- The role of nitric oxide in the nasal and paranasal cavities during the course of chronic and recurrent rhino-pharyngo-sinusal inflammation
- Normative chemoluminescent measurements of nitric oxide levels in the nasal cavities of adult and pediatric patients affected by chronic and recurrent rhino-pharyngeal and naso-sinusal inflammation;
- Evaluation of changes in nitric oxide level in patients with rhino-pharyngeal and naso-sinusal inflammation before and after pharmacological or surgical treatment (e.g. adenoidectomy) with the aim of identifying an objective means of monitoring treatment benefit.
- The role of some bacterial and viral etiological agents in determining recurrent upper airway infections, particularly adenotonsillar infections:
- Evaluation of the frequency of atypical bacteria in patients undergoing tonsillectomy, and their possible therapeutic consequences;
- Evaluation of the incidence and persistence of bacteremia in children undergoing adenoidectomy or adenotonsillectomy.
- New diagnostic pathways for evaluating functional phoniatric results in patients undergoing conservative surgery for the treatment of malignant laryngeal neoplasias
- Verification of long-term phoniatric results in patients undergoing reconstructive or conservative laryngectomy because of laryngeal carcinoma by means of objective GRBAS assessments and subjective VHI questionnaires concerning the quality of voice and the quality of life.
- The use of modern objective and subjective means of assessing the quality of voice and quality of life in patients affected by unilateral vocal cord paresis.
SCIENTIFIC PUBLICATIONS
The results of the research of Prof. Pasquale Capaccio are documented in 239 papers (IF 201,56) published in international scientific journals cited by PUBMED, uncited Italian and international journals, book chapters, official reports, the proceedings of international conferences, and presentations made at Italian and international congresses.
Prof. Capaccio is a Member of the Italian Society of Otorhinolaryngology, the Italian Society of Pediatric Otorhinolaryngology, the University Otorhinolaryngology Association. He is also a reviewer for the journals The Laryngoscope, European Archives of Otorhinolaryngology, the Indian Journal of Dental Research, and the Italian Journal of Maxillo-Odonto-Stomatology.
CLINICAL AND SURGICAL ACTIVITIES
Lead surgeon for more than 3000 otorhinolaryngologic surgical operations, particularly head-and-neck cancer and major salivary gland surgery using new mini-invasive and endoscopic techniques; functional endoscopic surgery of the nose and paranasal sinuses; and neonatal and pediatric otorhinolaryngologic surgery (endoscopic adenoid and tonsil surgery). Everyday medical/surgical work in the urgent and emergency departments of Fondazione IRCCS Ca’ Granda Policlinico.
In relation to the development of new endoscopic and mini-invasive surgical techniques for salivary gland disorders (more than 5000 extracorporeal salivary gland lithotripsy sessions, more than 500 sialendoscopic procedures, and 500 sialendoscopy-assisted conservative transoral and transfacial submandibular and parotid stone removal), Prof. Capaccio has organised and participated as a tutor or guest speaker in the following national and international events:
2002: Postgraduate Course “Minimally invasive management of salivary tumours & stones. London.
2003: International Course “Recent advances in the diagnosis and treatment of salivary gland disease”, Milan.
2005: International Postgraduate Course “Minimally invasive management of salivary tumours & stones”, Guy’s Hospital, London.
2006: Limited Attendance Workshop “Minimally invasive salivary tumours & stones. London.
2006-2008: Course “Novelties in the treatment of secretory disorders and dystonias of the head and neck”. Milan.
2006: 2nd International Course “Salivary gland disease”. Gargnano.
2008: International Congress: “Salivary gland disease. 1st International Accord on Modern Management”. Paris.
2009: Intensive course on surgical dissection in otorhinolaringology. Milan.
2011: Workshop teorico pratico di scialo endoscopia. Bologna.
2012: Workshop teorico pratico di scialo endoscopia. Bologna.
2013: Salivary gland disease, Royal Society of Medicine. London.
2013: IV Workshop teorico pratico di scialoendoscopia. Bologna.
2013: BAOMS Annual Scientific Meeting Royal College of Surgeons in Ireland. Dublin.
2014: Master biennale di II livello in Chirurgia e Patologia Orale. Parma.
2015: International Course StoneBreaker Vista Program. Wiesbaden, Germany.
2015-17: Postgraduate Course: Establishing a modern salivary Gland Practice. Guy’s Hospital and Edward VII’s Hospital, London.
MAIN PUBLICATIONS IN REVIEWED JOURNALS
- G. Broich, P. Capaccio, F. Ottaviani. Carcinoma of the vocal cord. Results after chordectomy. In Vivo 1994;8:703-706.
- N.S. Fracchiolla, L. Pignataro, P. Capaccio, D. Trecca, A. Boletini, A. Ottaviani, E. Polli, A.T. Maiolo, A. Neri. Multiple genetic lesions in laringea squamous cell carcinomas. Cancer 1995;75:1292-1301.
- F. Ottaviani, P. Capaccio, M. Campi, A. Ottaviani. Extracorporeal shockwave lithotripsy for salivary gland stones. Laryngoscope 1996;106:761-764.
- G. Pruneri, L. Pignataro, N.S. Fracchiolla, S. Ferrero, P. Capaccio, N. Carboni, A. Ottaviani, A.T. Maiolo, A. Neri, R. Buffa p53 protein expression in laryngeal squamous cell carcinomas bearing wild-type and mutated p53 gene. Histopathology 1996;28:513-519.
- L. Pignataro, P. Capaccio, G. Pruneri, N. Carboni, N.S. Fracchiolla, R. Richelda, G. Scaramellini, A. Neri, R. Buffa. p53 and cyclin D1 protein expression in glottis laryngeal squamous cell carcinomas involving the anterior commissure (pT1bN0M0). Int J Oncol 1996;9:553-557.
- L. Pignataro, N. Carboni, A. Pagliari, P. Capaccio, F. Ottaviani, G. Pruneri. Bcl-2 expression is related to poor differentiation and advanced clinical stage in laryngeal squamous cell carcinomas. J Chemotherapy 1997;9(2):115-16.
- P. Capaccio, N. Carboni, L. Pignataro, A. Scotti, F. Ottaviani, G. Pruneri. Cyclin D1, p53, MDM2, and ki67 proteins expression in preneoplastic lesions of the larynx. J Chemotherapy 1997;9(2): 113-14.
- A. De Vecchi, J.M. Morelli, E. Mascheroni, R. Parolari, P. Capaccio, G. Scaramellini. Nasal carriage of staph. Aureus in peritonitis and exit-site infections. Perit Dial Int 1997;17:205-206.
- N.S. Fracchiolla, G. Pruneri, L. Pignataro, N. Carboni, P. Capaccio, A. Boletini, R. Buffa, A. Neri. Molecular and immunohistochemical analysis of the bcl-1/CYCLIN D1 gene in laryngeal squamous cell carcinomas. Correlation of protein expression with lymph node metastases and advanced clinical stage. Cancer 1997;79:1114-21.
- G. Pruneri, L. Pignataro, N. Carboni, S. Luminari, P. Capaccio, A. Neri, R. Buffa. MDM-2 oncoprotein overexpression in laryngeal squamous cell carcinoma: association with wild-type p53 accumulation. Mod Pathol 1997;10:1-8.
- F. Ottaviani, P. Capaccio, R. Rivolta, P. Cosmacini, L. Pignataro, D. Castagnone. Salivary gland stones: US evaluation in shock wave lithotripsy. Radiology 1997;204:437-441.
- P. Capaccio, G. Pruneri, N. Carboni, A.V. Pagliari, R. Buffa, A. Neri, L. Pignataro, A. Ottaviani. Cyclin D1 protein expression is related to clinical progression in laryngeal squamous cell carcinomas. J Laryngol Otol 1997;III:622-626.
- L. Pignataro, P. Capaccio, N. Carboni, G. Pruneri, A. Ottaviani, R. Buffa, G. Broich. P53 and cyclin D1 protein expression in carcinomas of the parotid gland. Anticancer Res 1998;18:1287-1290.
- L. Pignataro, P. Capaccio, G. Pruneri, N. Carboni, R. Buffa, A. Neri, A. Ottaviani. The predictive value of p53, MDM-2, cyclin D1 and ki67 in the progression from low grade dysplasia towards carcinoma of the larynx. J Laryngol Otol 1998;112:455-459.
- L. Pignataro, G. Pruneri, N. Carboni, P. Capaccio, B.M. Cesana, A. Neri, R. Buffa. Clinical relevance of cyclin D1 protein overexpression in laryngeal squamous cell carcinomas. J Clin Oncol 1998;16:3069-3077.
- N.S. Fracchiolla, P. Capaccio, N. Carboni, A.V. Pagliari, A. Neri, D. Ronchetti, G. Pruneri, M.G. Silvotti, L. Pignataro, R. Buffa, G. Broich. Immunohistochemical and molecular analysis of bax, bcl-2 and p53 genes in laryngeal squamous cell carcinomas. Anticancer Res 1999;19:1043-1051.
- P. Capaccio, G. Pruneri, N. Carboni, A.V. Pagliari, M. Quatela, B. Cesana, L. Pignataro. Cyclin D1 expression is predictive of occult metastases in head and neck cancer patients with clinically negative cervical lymph nodes. Head Neck 2000;22: 234-240.
- L. Pignataro, P. Capaccio, C.B. Neglia, A. Ottaviani. Clinical experience with the treatment of T1b glottis cancer by means of horizontal glottectomy.Eur Arch Oto-Rhino-Laryngol 2000;257: 216-218.
- A. Zaghis, L. Grillo della Berta, P. Capaccio, L. Pignataro. Myringoplasty in pediatric age: anatomical and functional results.J Laryngol Otol 2001;115:369-373.
- F. Ottaviani, P. Marchisio, E. Arisi, P. Capaccio. Extracorporeal shcok-wave lithotripsy for pediatric salivary calculi. Acta Otolaryngol 2001;121: 873-876.
- P. Capaccio, A. D’Arminio Monforte, M. Moroni, F. Ottaviani. Salivary stone lithotripsy in the HIV patient. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;93:525-527.
- P. Capaccio, A. Peri, P. Fociani, A. Ferri, F. Ottaviani. Flexible argon plasma coagulation treatment of obstructive tracheal metastatic melanoma. Am J Otolaryngol 2002;23:253-255.
- F. Ottaviani, C.B. Neglia, A. Scotti, P. Capaccio. Aracnoid cyst of the cranial posterior fossa causing sensorineural hearing loss and tinnitus. A case report. Eur Arch Otolaryngol 2002;259:306-308.
- F. Ottaviani, A. Schindler, P. Capaccio, G. Bianchi Porro. A new therapy for orolaryngeal manifestations of Crohn’s disease. Ann Otol Rhinol Laryngol 2003;112:37-39.
- A. Zaghis, L. Todini, P. Capaccio, L. Grillo della Berta, L. Pignataro. Ossified versus patent coclea. Objective and subjective results of partial drill out of the basal turn. J Otolaryngol 2003;32: 160-7.
- F. Ottaviani, P. Capaccio, BM Cesana, R. Manzo, A. Peri. Argon plasma coagulation in the treatment of non allergic hyperthrophic inferior nasal turbinates. Am J Otolaryngol 2003;24: 306-10.
- P. Capaccio, F. Ottaviani, R. Manzo, A. Schindler, B. Cesana. Extracorporeal lithotripsy for salivary calculi: a long term clinical experience. The Laryngoscope 2004;114: 1069-1073.
- P. Capaccio, M. Paglia, D. Minorati, R. Manzo, F. Ottaviani. Diagnosis and therapeutic management of iatrogenic parotid sialocele. Ann Otol Laryngol Rhinol 2004;113: 562-564.
- P. Capaccio, A. Bottero, M. Pompilio, F. Ottaviani. Conservative transoral removal of hilar submandibular salivary calculi. The Laryngoscope 2005;115:750-752.
- P. Capaccio, F. Ottaviani, V. Cuccarini, U. Ambrosetti, E. Fagnani, A. Bottero, S. Cenzuales, B.M. Cesana, L. Pignataro. Sudden hearing loss and MTHFR 677C>T/1298>C gene polymorphisms. Genet Med 2005;7:206-8.
- P. Capaccio, F. Ottaviani, V. Cuccarini, S. Cenzuales, B.M. Cesana, L. Pignataro. Association between methylenetetrahydrofolate reductase polymorphisms, alcohol intake and oropharyngolaryngeal carcinoma in northern Italy. J Laryngol Otol 2005;119:371-6.
- P. Capaccio, F. Ottaviani, V. Cuccarini, U. Ambrosetti, E. Fagnani, A. Bottero, S. Cenzuales, B.M. Cesana, L. Pignataro. Methylenetetrahydrofolate reductase gene mutations as risk factors for sudden hearing loss. Am J Otolaryngol 2005;26:383-7.
- A. Schindler, P. Capaccio, F. Ottaviani. Videoendoscopic surgery for inaccessible glottis lesions. J Laryngol Otol 2005;119:899-902 (2007: IF 0,501).
- A. Schindler, A. Canale, A.L. Cavalot, R. Albera, P. Capaccio, F. Ottaviani, O. Schindler. Intensity and fundamental frequency control in tracheoesophageal voice. Acta Otorhinolaryngol Ital 2005;25:240-4.
- A. Schindler, A. Bottero, P. Capaccio, D. Ginocchio, F. Adorni. Vocal improvement after voice therapy in unilateral vocal fold paralysis. J Voice 2006;22:113-118.
- P. Capaccio, V. Cuccarini, V. Benicchio, D. Minorati, F. Spadari, F. Ottaviani. Treatment of iatrogenic submandibular sialocele with botulinum toxin. Br J Oral Maxillofac Surg 2007;45:415-7.
- P. Capaccio, F. Ottaviani, V. Cuccarini, A Bottero, A. Schindler, B.M. Cesana, S. Censuales, L. Pignataro. Genetic and acquired prothrombotic risk factors and sudden hearing loss. Laryngoscope 2007;117:547-551.
- G. Cammarota, G. Masala, R. Cianci, D. Palli, P. Capaccio, A. Schindler, L. Cuoco, J. Galli, E. Ierardi, O. Cannizzaro, M. Caselli, MP. Dorelli, B. Bendinelli, G. Gasbarrini. Reflux symptoms in professional opera choristers. Gastroenterology 2007;132:890-8.
- A. Schindler, V. Cuccarini, A. Bottero, C. Dobrea, P. Capaccio, F. Ottaviani. Long-term vocal functional results after glottectomy: a multi-dimensional analysis. Eur Arch Otorhinolaryngol 2007;264:1039-44.
- A. Schindler, P. Capaccio, P. Maruzzi, D. Ginocchio, A. Bottero, F. Ottaviani. Preliminary considerations on the application of the voice handicap index to pediatric dysphonia. Acta Otorhinolaryngol Ital 2007;27:22-6.
- D. Pagani, P. Capaccio, W. Fontanella, G. Sambataro, G. Broich, L. Pignataro. Vertical platysma myocutaneous flap reconstruction for T2-staged oral carcinoma. Anticancer Res 2007;27:2961-4.
- P. Capaccio. LM Gaini, D. Pagani, G. Sambataro, L. Pignataro. Videosialoendoscopic assessment of bilateral atresia of the Wharton’s duct orifice in an infant. J Pediatr Surg 2007;42:E5-7.
- P. Capaccio, S. Torretta, F. Ottaviani, G. Sambataro, L. Pignataro. Modern management of obstructive salivary diseases. Acta Otorhinolaryngologica Ital 2007;27:161-72.
- L. Drago, S. Esposito, E. De Vecchi, P. Marchisio, F. Blasi, E. Baggi, P. Capaccio, L. Pignataro. Detection of respiratory viruses and atypical bacteria in children’s tonsils and adenoids. J Clin Microbiol 2008;6:369-370.
- P. Marchisio, A. Selicorni, L. Pignataro, D. Milani, E. Baggi, L. Lambertini, E. Dusi, L. Villa, P. Capaccio, M. Cerutti, S. Esposito, N. Principi. Otitis media with effusion and hearing loss in children with Cornelia De Lange Syndrome. Am J Med Genet A 2008;146:426-32.
- P. Capaccio, V. Cuccarini, F. Ottaviani, D. Minorati, G. Sambataro, P. Cornalba, L. Pignataro. Comparative ultrasonographic, magnetic resonance sialographic, and videoendoscopic assessment of salivary duct disorders. Ann Otol Rhinol Laryngol 2008;117:245-252.
- P. Capaccio, S. Torretta, M. Osio, D. Minorati, F. Ottaviani, G. Sambataro, C. Nascimbene, L. Pignataro. Botulinum toxin therapy: a tempting tool in the management of salivary duct disorders.Am J Otolaryngol 2008;29:333-338.
- S. Esposito, P. Marchisio, P. Capaccio, M. Bellasio, F. Corti, E. Dusi, F. Blasi, L. Pignataro. Role of atypical bacteria in children undergoing tonsillectomy because of severely recurrent acute tonsillopharyngitis. Eur J Clin Microbiol Infect Dis 2008;27:1233-1237.
- P. Capaccio, I.A. Clemente, P. Marchisio, A. Selicorni, S. Esposito, L. Pignataro. Videoendoscopic rehabilitation of iatrogenous Stensen duct-acquired atresia in a patient with ring chromosome 21 syndrome and drooling. J Ped Surg 2008;43:E17-20.
- S. Esposito, P. Marchisio, P. Capaccio, M. Bellasio, M. Semino, E. Dusi, R. Colmbo, L. Pignataro, N. Principi. Risk factors for bacteremia during and after adenoidectomy and/or adenotonsillectomy. J Infection 2009;58:113-118.
- F. Ottaviani, P. Capaccio, F. Villani, M. Banderali, G. Pruneri, M. Klinger, L. Pignataro. Bona fide primary Merkel cell carcinoma of an intraparotid lymph node in a HIV positive patient. Int J Surg Pathol 2009; jan 14 (Epub).
- P. Capaccio, F. Ottaviani, V. Cuccarini, M. Corbellino, C. Parravicini, S. Menzo, A. Schindler, L Pignataro. Surgery and topic cidofovir for nasal squamous papillomatosis in HIV+ patient. Eur Arch Otorhinolaryngol 2009;266:937-939.
- H. Iro, J. Zenk, M.P. Escudier, O. Nahlieli, P. Capaccio, P. Katz, J. Broen, M. McGurk. Outcome of minimally invasive management of salivary calculi in 4691 patients. Laryngoscope 2009;119:263-268.
- A. Schindler, E. Favero, P. Capaccio, R. Albera, A.L. Cavalot, F. Ottaviani. Supracricoid laryngectomy: age influence on long-term functional results. Laryngoscope 2009;119:1218-1225.
- R. Marino, P. Capaccio, L. Pignataro, F. Spadari. Burning mouth syndrome: the role of contact hypersensitivity. Oral Disease 2009;15:255-258.
- P. Capaccio, V. Cuccarini, F. Ottaviani, N.S. Fracchiolla, A. Bossi, L. Pignataro. Prothrombotic gene mutations in patients with sudden sensorineural hearing loss and cardiovascular thrombotic disease. Ann Otol Rhinol Laryngol 2009;118:205-210.
- L. Pignataro, S. Torretta, M.C. Pietrogrande, R.M. Delle Piane, P. Pavesi, A. Bossi, L. Drago, P. Capaccio. Outcome of tonsillectomy in selected patients with PFAPA syndrome. Arch Otolaryngol Head Neck Surg 2009;118:205-210.
- D. Pagani, M. Bellinvia, P. Capaccio, B. Scoppio, L. Brambilla, L. Pignataro. An unusual case of a parotid mass in an immunocompetent host: classic Kaposi’s sarcoma. Tumori 2009;95:248-250.
- P. Capaccio, S. Torretta, L. Pignataro. Extracorporeal lithotripsy techniques for salivary stones. Otolaryngol Clin North Am 2009;42:1139-1159.
- P. Capaccio, S. Torretta, L. Pignataro. The role of adenectomy for salivary gland obstructions in the era of sialoendoscopy and lithotripsy. Otolaryngol Clin North Am 2009;42:1161-1171.
- L. Pignataro, S. Torretta, P. Capaccio, S. Esposito, P. Marchisio. Unusual otolaryngologycal manifestations of certain sistemi bacterial and fungal infections in children. Int J Pediatr Otorhinolaryngol 2009;73 Suppl 1:S33-7.
- P. Marchisio, S. Torretta, P. Capaccio, S. Esposito, E. Dusi, E. Nazzari, A. Bossi, L. Pignataro, N. Principi. Clinical assessment of adenoidal obstruction based on the nasal obstruction index is no longer useful in children. Otolaryngol Head Neck Surg 2010;142:237-241.
- P. Marchisio, S. Bianchini, P. Capaccio, S. Esposito, M. Fusi, E. Nazzari, S. Torretta, N. Principi. Insights into infectious otitis media. Int J Immunopathol Pharmacol 2010;23(1 Suppl):20-23.
- L. Zhang, M. Escudier, J. Brown, P. Capaccio, L. Pignataro, M. McGurk. Long-term out come after intraoral removal of large submandibular gland calculi. Laryngoscope 2010;120:964-966.
- S. Torretta, A. Bossi, P. Capaccio, P. Marchisio, S. Esposito, A. Brevi, L. Pignataro. Nasal nitric oxid in children with adenoidal hypertrophy: a preliminary study. Int J Pediatr Otorhinolaryngol 2010;74:689-693.
- M.P. Escudier, J.E. Brown, V. Putcha, P. Capaccio, M. McGurk. Factor influencing the outcome of extracorporeal shock wave lithotripsy in the management of salivary calculi. Laryngoscope 2010;120:1545-1549.
- R. Marino, S. Torretta, P. Capaccio, L. Pignataro, F. Spadari. Different therapeutic strategies for burning mouth syndrome: preliminary data. J Oral Pathol Med 2010 Aug 2 (Epub ahead of print).
- D. Pagani, P. Capaccio, A. Balzani, L. Pignataro. Dysphagia and submandibular swelling. Eagle syndrome. J Am Dent Assoc 2010; 141:1089-93.
- S. Torretta, L. Pignataro, P. Capaccio, A. Brevi, R. Mazzola. The buccal fat: a convenient and effective autologus option to prevent Frey syndrome and for facial contour parotidectomy. Plast Reconstr Surg 2011; 127:998.
- P. Capaccio, I.A. Clemente, M. McGurk, A. Bossi, L. Pignataro. Transoral removal of hiloparenchymal submandibular calculi: a long-term clinical experience. Eur Arch Otorhinolaryngol 2011; 268:1081-6.
- P. Capaccio, I.A. Clemente, M. Mantovani, P. Marchisio, S. Esposito, L. Pignataro. Submental dermoid cyst: a rare clinical entità in early pediatric age. Pediatr Med Chir 2011; 33:92-4.
- S. Torretta, L. Pignataro, P. Capaccio, A. Brevi, R. Mazzola. Fat injections for the management of post-parotidectomy Frey syndrome: a technical note. J Craniomaxillofac Surg 2012; 40:173-6.
- P. Capaccio, L. Pignataro, L.M. Gaini, P.E. Sigismund, C. Novembrino, R. De Giuseppe, V. Uva, A. Tripodi, F. Bamonti. Unbalanced oxidative status in idiopathic sudden sensorineural hearing loss. Eur Arch Otorhinolaryngol 2012;269:449-53.
- P. Capaccio, N. Luca, P.E. Sigismund, L. Pignataro. Recurrent inflammation of accessory parotid tissue associated with unilateral parotid gland aplasia: diagnostic and therapeutic implications. Eur Arch Otorhinolaryngol 2012;269:1551-1554.
- P. Capaccio, P.E. Sigismund, N. Luca, P. Marchisio, L. Pignataro. Modern management of juvenile recurrent parotitis. J Laryngol Otol 2012;16:1-7.
- P. Marchisio, A. Varricchio, E. Baggi, S. Bianchini, M.E. Capasso, S. Torretta, P. Capaccio, C. Gasparini, F. Patria, S. Esposito, N. Principi. Hypertonic saline is more effective than normal saline in seasonal allergic riniti in children. Int J Immunopathol Pharmacol 2012;25:721-730.
- P. Capaccio, G.A. Marciante, M. Gaffuri, F. Spadari. Subamdnibular swelling: tooth or salivary stone? Indian J Dent Res 2013;24:381-383.
- S. Torretta, P. Marchisio, M. Gaffuri, P. Capaccio, S. Esposito, L. Pignataro. Step-by-step iconographic description of a prolonged but still favourable course of orbital cellulitis in a child with acute rhinosinusitis: an iconographic case study. Ital J Ped 2014 Mar 4;40(1):25.
- A.Tripodi, P. Capaccio, L. Pignataro, V. Chantarangkul, M. Menegatti, F. Bamonti, M. Clerici, R. De Giuseppe, F. Peyvandi. Thrombin generation in patients with idiopathic sudden sensorineural hearing loss. Thromb Res 2014 133(6):1130-4.
- P. Capaccio, M. Gaffuri, L.Pignataro. Sialendoscopy-assisted transfacial removal of parotid stones. J Craniomaxillofac Surg 2014;42(8):1964-9.
- Torretta, P. Marchisio, L. Drago,P. Capaccio, E. Baggi, L. Pignataro. The presence of biofilm-producing bacteria on tonsils is associated with increased exhaled nitric oxide levels: preliminary data in children who experience recurrent exacerbations of chronic tonsillitis. J Laryngol Otol 2015 Mar;129(3):267-72.
- Tagliabue, S.H. Elrefaey, F. Peccatori, G. Favia, V. Navach, L. Pignataro, P. Capaccio, M. Venturino, S. Tredici, D. Alterio, F. Mosca, L. Pugni, G. Scarfone, M. Cossu Rocca, L. Calabrese. Tongue cancer during pregnancy: Surgery and more, a multidisciplinary challenge. Crit Rev Oncol Hematol 2016 98:1-11.
- Capaccio, S. Torretta, G.A. Marciante, P. Marchisio, S. Forti, L. Pignataro. Endoscopic adenoidectomy in children with otitis media with effusion and mild hearing loss. Clin Exp Otol 2016 9:33-8.
- Torretta, P. Marchisio, P. Capaccio, L. Pignataro. Nasal nitric oxide in children with recurrent acute otitis media. J Biol Reg Homeostat Ag 2016 30:285-290.
- Torretta, P. Marchisio, E. Iofrida, P. Capaccio, L. Pignataro. Serum 25-hydroxyvitamin D levels in children with recurrent tonsillitis living in Milan. J Biol Reg Homeostat Ag 2015 29:925-30.
- Taschieri, S. Torretta, S. Corbella, M. Del Fabbro, L. Francetti, A. Lolato, P. Capaccio. Pathophysiology of sinusitis of odontogenic origin: a narrative review. J Invest Clin Dent 2017 May;8(2). doi: 10.1111/jicd.12202. Epub 2015 Dec 14. Review.
- A. Gallo, M. Benazzo, P. Capaccio, L. De Campora, M. De Vincentiis, M. Fusconi, S. Martellucci, G. Paludetti, E. Pasquini, R. Puxeddu, R. Speciale. Sialoendoscopy: state of the art, challenges and further perspectives. Round Table, 101(st) SIO National Congress, Catania 2014. Acta Otorhinolaryngol Ital 2015 Oct;35(4):217-33. Review.
- Capaccio, M. Gaffuri, S. Torretta, L. Pignataro. Sialendoscopy-assisted transfacial surgery for the removal of an iatrogenic foreign body in Stensen’s duct: a stone and broken wire basket. J Laryngol Otol 2016 May;130(5):501-5.
- Capaccio, M. Gaffuri, L. Pignataro, F. Assandri, P. Pereira, G. Farronato. Recurrent parotid swelling secondary to masseter muscle hypertrophy: a multidisciplinary diagnostic and therapeutic approach. Cranio 2016 Nov;34(6):388-394.
- Torretta, P. Marchisio, G. Succo, P. Capaccio, L. Pignataro. Nasopharyngeal fiberendoscopy in children: a survey of current Italian pediatric otolaryngological practices. Ital J Pediatr 2016 Mar 1;42:24.
- Gallo, P. Capaccio, M. Benazzo, L. De Campora, M. De Vincentiis, P. Farneti, M. Fusconi, M. Gaffuri, F. Lo Russo, S. Martellucci, F. Ottaviani, G. Pagliuca, G. Paludetti, E. Pasquini, L. Pignataro, R. Puxeddu, M. Rigante, E. Scarano, E. Sionis, R. Speciale, P. Canzi. Outcomes of interventional sialendoscopy for obstructive salivary gland disorders: an italian multicentre study. Acta Otorhinolaryngol Ital 2016 36:479-485.
- Capaccio, S. Torretta, D. Di Pasquale, V. Rossi, L. Pignataro. The role of interventional sialendoscopy and intraductal steroid therapy in patients with recurrent sine causa sialadenitis: a prospective cross-sectional study. Clin Otolaryngol 2017 Feb;42(1):148-155.
- Capaccio, P. Canzi, M. Gaffuri, A. Occhini, M. Benazzo, F. Ottaviani, L. Pignataro. Modern managemrnt of paediatric obstructive salivary disorders: long-term clinical experience. Acta Otorhinolaryngol Ital 2017 37:160-167.
- Canzi, S. Cacciola, P. Capaccio, F. Pagella, A. Occhini, L. Pignataro, M. Benazzo. Interventional sialendoscopy for radioiodine-induced sialadenitis: quo vadis? Acta Otorhinolaryngol Ital 2017 37:155-59.
- Capaccio, M. Gaffuri, V. Rossi, L. Pignataro. Sialendoscope-assisted transoral removal of hilo-parenchymal sub-mandibular stones: surgical results and subjective scores. Acta Otorhinolaryngol Ital 2017 37:122-127.
- Capaccio, S. Torretta, L. Pignataro, M. Koch. Salivary lithotripsy in the era of sialendoscopy. Acta Otorhinolaryngol Ital 2017 37:113-121.
- Capaccio, P. Canzi, S. Torretta, V. Rossi, M. Benazzo, A. Bossi, C. Vitali. Combined interventional sialendoscopy and intraductal steroid therapy for recurrent sialadenitis in Sjogren’s syndrome. Results of a pilot monocentric trial. Clin Otolaryngol 2017 jun 5 doi:10.1111/coa. 12911 (Epub ahead of print).
- Conte, F. Di Berardino, C. Sina, D. Zanetti, E. Scola, C. Gavagna, L. Gaini, G. Palumbo, P. Capaccio, F. Triulzi. MR imaging in sudden sensorineural hearing loss. Time to talk. AJNR Am J Neuroradiol 2017 may 25 doi: 10.3174/ajnr.A5230 (Epub ahead of print).